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--Contact Information-- |
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| A401 Wells Hall |
| Department of Statistics and Probability, Michigan State University |
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East Lansing, Michigan, 48824 |
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Email: lishaoyu AT stt dot msu dot edu |
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Phone: (517) 285-5081 |
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--Reseach Interests-- |
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-Statistical genetics, gene-gene interaction, genomewide association study, genomewide rare variants detection |
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-Statistical genomics, eQTL mapping, microarray data analysis, systems biology, gene set enrichment analysis, genetic network inference |
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-Bayesian statistical method and its application in gene expression data analysis |
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--Education-- |
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| -Dual major PhD candidate in Statistics and Quantitative Biology, Michigan State University, expected in 2011 |
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-Master, Department of Mathematics, Huazhong University of Science and Technology, Wuhan, China. 2003-2006 |
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-B.S., Department of Mathematics, Huazhong University of Science and Technology, Wuhan, China. 1999-2003 |
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--University experience-- |
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| -Fall 2010 Teaching Assistant, Recitation Instructor of STT 200 |
| -Summer 2010 Independent Instructor of STT 200 |
| -Spring 2010 Research Assistant |
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-Fall 2009 Teaching Assistant, Recitation Instructor of MTH 112 |
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-Summer 2009 Research Assistant |
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-Spring 2009 Teaching Assistant/Research Assistant |
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-Fall 2008, Summer 2008, Spring 2008 Research Assistant |
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-Fall 2007,Summer 2007, Spring 2007 Teaching Asssitant, Recitation Instructor of STT 200 |
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-Spring 2007, Teaching Assistant, Recitation Instructor of STT 201 |
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-Fall 2006, Teaching Assistant, Recitation Instructor of STT 315 |
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--Publications and working papers-- |
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| Invited Book Chapters |
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1. Cui, Y.H., G.X. Li, S.Y. Li and R.L. Wu. (2010) Designs for Linkage Analysis and Association Studies of Complex Diseases. In: Statistical Methods in Molecular Biology (Eds.: H. Bang, X.K. Zhou, H.L. Van Epps and M. Mazumdar) Humana Press. |
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| Peer-referred journal Articles |
| 2. Li, S.Y., B. Williams and Y.H. Cui (2011) A combined p-value approach to infer pathway regulations in eQTL mapping. Statistics and Its Interface (in press) |
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3. Li, S.Y., Q. Lu and Y.H. Cui. (2010) A systems biology approach for identifying novel pathway regulators in an eQTL mapping study. Journal of Biopharmaceutical Statistics 20(2): 373–400. |
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4. Li, S.Y., Q. Lu, W. Fu, R. Romero and Y.H. Cui. (2009) A regularized regression approach for dissecting genetic conflicts that increase disease risk in pregnancy. Statistical Applications in Genetics and Molecular Biology. Vol. 8 : Iss. 1, Article 45. |
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5. Cui, Y.H., S.Y. Li, and G.X. Li, (2008) Functional Mapping Imprinted Quantitative Trait Loci Underlying Developmental Characteristics. Theoretical Biology and Medical Modeling 5:6. |
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6. Li, S.Y., C.H. Liu, (2006) Empirical Bayesian Estimator for the parameter of the linear exponential model. Journal of Huazhong University of Science and Technology 34: 3 (English Abstract) |
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| Working papers |
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7. Li, S.Y. and Y.H Cui, Gene-centric gene-gene interactions: a model-based kernel machine method. (submitted) |
| 8. Li, S.Y. and Y.H. Cui, A gene-centric approach for detecting gene-gene interactions in case-control studies. (in progress) |
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9. Li, S.Y. and Y.H. Cui. Comparison of statistical methods for genome-wide rare variants detection.(in progress) |
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10. Li, S.Y. and Y.H. Cui. A gene-centric epistasis analysis identified novel gene-gene interactions associated with responses to small-molecule drugs in yeast. (in progress) |
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--Conference experience-- |
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| -(Poster) Systems Biology Symposium, Michigan State University, East Lansing, MI, Oct. 2010 |
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-(Poster) "A kernel machine method for gene-centric gene-gene interaction", Quantitative Biology Initiative graduate student poster session, East Lansing, MI, August 2010 |
| -(Invited speaker) "Kernel machine methods in eQTL mapping", ICSA Applied Statistics Symposium, Indianapolis, IN, June 2010 |
| -(Contributed speaker) "Enriching our knowledge in gene regulation via eQTL mapping: a combined p-value approach", ENAR Spring Meeting, New Orleans, LA, March 2010 |
| -(Poster) "A systems biology approach for identifying novel pathway regulators in eQTL mapping", Quantitative Biology Initiative Symposium, East Lansing, MI, August 2009 |
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-(Committee selected student talk) "A systems biology approach for identifying novel pathway regulators in eQTL mapping", Growth Factor and Signal Transduction Symposium (on Systems Biology: Integrative, Comparative, and Multi-scale Modeling), Iowa State University, June 2009 |
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-(Contributed speaker) "A regularized regression approach for dissecting genetic conflicts that increase disease risk in pregnancy", ENAR Spring Meeting, San Antonio, TX, March 2009 |
| -3rd Midwest Statistics Research Colloquium, The University of Chicago, Chicago, IL, March 26-27, 2010 |
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-Midwest Conference on Mathematical Methods for Images and Surfaces, East Lansing, MI, April 18-19, 2009 |
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-Midwest Conference on System Biology, East Lansing, MI, Oct. 27-Oct. 28, 2007 |
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--Academic awards-- |
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-Summer Research Fellowship, The college of Natural Science, Michigan State University (May-August, 2010) |
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-Graduate Student travel Award, Michigan State University (March, 2010) |
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-Travel grant, Growth Factor and Signal Transduction Symposium (on Systems Biology: Integrative, Comparative, and Multi-scale Modeling), Iowa State University (June, 2009) |
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-Travel Award (Stapleton Fund), Michigan State University (March, 2009) |
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-Graduate Research Fellowship award, Quantitative Biology Initiative, Michigan State University (2008-2009) |
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-QB Recruiting Cash Award, Quantitative Biology Initiative, Michigan State University (2008) |
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-Summer Research Fellowship, The College of Natural Science, Michigan State University (May-August, 2008) |
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-Outstanding Graduate Student Scholarships, Huazhong University of Science & Technology (2003-2006) |
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-Scholarships for Academic Excellence, Huazhong University of Science & Technology (2000-2003) |
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--Professional Membership-- |
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-East Northern American Region/International Biometric Society (2010-) |
| -American Statistical Association (2010-) |
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-International Chinese Statistical Association (2010-) |
| -Institute of Mathematical Statistics (2008-) |
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--computer skills-- |
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| -Statistical software: R/S-Plus, SAS SPSS and Mintab |
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-Data and file rocessing: Excel, Perl and Latex |
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-Operation System: Unix and Windows |
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-Language: C and Fortran |
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